Cardiac troponin I (cTnI) is a cardiac specific biomarker that is released during myocardial necrosis; it reaches a peak value in blood after about 11 h [1]. Compared to myoglobin and creatine-kinase-MB, cTnI is more sensitive and specific to acute myocardial infarction (AMI) [2].

As POC assays can provide troponin results within 20 min, and can be used proximate to patient care, improvements in the efficiency of assessment of patients with suspected acute coronary syndrome is possible, particularly with new high-sensitivity assays. Keywords: emergency department, assessment.

Low concentrations of cTnI can be analysed by using high sensitivity cardiac troponin (hs-cTnI) assays which meet the criteria defined by IFCC and ESC. PATHFAST™ provides high accuracy and precision of test results similar to central lab analyser, combined with the flexibility of a POCT assay below 17 minutes out of whole blood and plasma by ...

PoCT Cardiac Troponin Abbott i-STAT cTnI Presenting Patient—symptoms suggestive of ACS Careful clinical history. Evaluation to exclude other causes of Chest Pain and likelihood of evolving ACS. Initial PoCT troponin test on presentation.

Until now, high-sensitivity cardiac troponin (hs-cTn) assays were mainly developed for large central laboratory platforms. This study aimed to assess the clinical performance of a point-of-care (POC)-hs-cTnI assay in patients with suspected myocardial infarction (MI).

Many authors have suggested that the development of Point-Of-Care-Testing (POCT) methods for cTnI and cTnT with high analytical sensitivity could represent a fundamental progress because these methods could further reduce the TAT of cTnI …

Sep 21, 2021 · Measurement of cardiac troponin I (cTnI) should be feasible for point-of-care testing (POCT) to diagnose acute myocardial infarction (AMI). Lateral flow immunoassays (LFIAs) have been long...

May 17, 2023 · The POCT method called “Siemens POC Atellica ® VTLi hs-cTnI” adopts an innovative system that uses Magnotech® type biosensors to separate the cTnI fraction, bound by antibodies to magnetic beads, from the free fraction, and detects the signal using the imaging technique called Frustrated Total Internal Reflection (FTIR) (30).

Apr 2, 2025 · SpinChip Diagnostics, in which bioMérieux has held an approximate 20% stake since March 2024, has just published results showing the very good performance of its high-sensitivity Point-of-Care (POC) cardiac troponin I (hs-cTnI) assay.

The measurement of cardiac troponin as either cardiac troponin T (cTnT) or cardiac troponin I (cTnI) is the gold standard biochemical test for the detection of clinically significant myocardial injury and the definitive test to confirm the diagnosis of acute myocardial infarction (AMI) .