DNA repair protein XRCC1, also known as X-ray repair cross-complementing protein 1, is a protein that in humans is encoded by the XRCC1 gene. XRCC1 is involved in DNA repair, …

Nov 22, 2021 · We show that aberrant PARP1 activity suppresses transcriptional recovery during base excision repair by promoting excessive recruitment and activity of the ubiquitin protease …

Mar 30, 2025 · XRCC1 (X-Ray Repair Cross Complementing 1) is a Protein Coding gene. Diseases associated with XRCC1 include Spinocerebellar Ataxia, Autosomal Recessive 26 …

XRCC1 is a molecular scaffold protein that interacts with multiple enzymatic components of DNA single-strand break repair (SSBR) including DNA kinase, DNA phosphatase, DNA …

X-ray cross complementing protein 1 (XRCC1) is a DNA repair scaffold that supports base excision repair and single strand break repair, and is also a participant in other repair pathways.

XRCC1 is an HSP90 client protein that protects XRCC1 from proteasome-mediated degradation. Chinese Han people with rs1799782 TT/CT genotype of XRCC1 gene may have increased …

X-ray cross complementing group 1 protein (XRCC1) forms enzyme complexes optimized for single-strand break repair, but participates in other repair pathways as well. Available …

Sep 1, 2019 · XRCC1 is a molecular scaffold protein that interacts with multiple enzymatic components of DNA single-strand break repair (SSBR) including DNA kinase, DNA …

However, DNA repair mechanisms often hinder treatment efficacy, notably Base Excision Repair (BER), mediated by the X-ray Repair Cross Complementing 1 (XRCC1) protein. This review …

Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (PubMed: 11163244, PubMed: 28002403).