In the present study, we describe a set of leukemia and lymphoma cell lines, which are carefully characterized for WT1’s unique properties and thoroughly screened for sequence alterations in …

We evaluated the WT1 protein expression level in various types of STS and elucidated the value of WT1 as a prognostic factor and a possible therapeutic target. Immunohistochemical staining …

WT1 expression ≥ 100 copies was defined as WT1 positive. Meanwhile, patients with WT1 mutation were divided into WT1 high and low expression groups according to the ROC curve …

Wilms tumor protein (WT33) is a protein that in humans is encoded by the WT1 gene on chromosome 11p. [5][6][7][8] This gene encodes a transcription factor that contains four zinc …

Mar 17, 2006 · WT1 was first identified as a tumor suppressor involved in the development of Wilms’ tumor. Recently, oncogenic properties of WT1 have been demonstrated in various …

The difference in WT1 expression was highly significant between serous and other types of tumors in all sites (p<0.0001, chi-square test), although the level of WT1 expression was …

What are the WT1-related Wilms tumor (WT) syndromes? The WT1-related Wilms tumor (WT) syndromes are a group of hereditary disorders caused by alterations in a gene known as WT1. …

Apr 6, 2021 · Wilm’s tumor 1 (WT1), a zinc-finger transcription factor and an epigenetic modifier, is frequently overexpressed in several hematologic disorders and solid tumors, and it has been …

Jun 15, 2006 · In this issue of Blood, Simpson and colleagues describe the presence of the antiapoptotic gene A1/Bfl1 as a WT1 target gene that mediates granulocytic differentiation and …

We characterized the most abundant population of RP mesen-chymal stromal cells in the spleen as fibroblasts specifically ex-pressing the transcription factor Wilms’ Tumor 1 (WT1). RP fibro …