Aug 16, 2012 · Microbial ligation of pattern-recognition receptors, such as TLR4, CD14, and dectin 1, is now known to induce the activation of calcineurin/NFAT signaling in myeloid cells, …

NFAT pour Nuclear factor of activated T-cells (facteur nucléaire des lymphocytes T activés) est un ensemble de protéines de la famille des facteurs de transcription impliquée dans la réponse …

Nuclear factor of activated T-cells (NFAT) is a family of transcription factors shown to be important in immune response. One or more members of the NFAT family is expressed in most cells of …

Here, we review the role of the Ca 2+-calcineurin–NFAT signaling pathway in health and diseases, focusing on the STIM and Orai1, and discuss the deregulated calcium-mediated …

Aug 16, 2012 · The calcineurin/nuclear factor of activated T cells (NFAT) signaling pathway mediates multiple adaptive T-cell functions, but recent studies have shown that …

Mar 10, 2020 · Here, we review the role of the Ca 2+-calcineurin-NFAT signaling pathway in health and diseases, focusing on the STIM and Orai1, and discuss the deregulated calcium …

Jun 1, 2005 · Experimental evidence indicates that, during T-cell development, calcium–calcineurin–NFAT signalling is a key regulator of positive selection. NFAT2 and …

This review discusses the dynamic interactions between the NFAT signalling pathway and viral pathogens. It also addresses several drugs and agents that can target the NFAT signalling …

Jan 30, 2014 · The calcineurin/nuclear factor of activated T cells (NFATs) signaling pathway plays a central role in T cell mediated adaptive immune responses, but a number of recent studies …

Apr 19, 2002 · The four genes encoding the cytoplasmic subunits of NFAT transcription complexes play critical roles in regulating the genes necessary for interactions with cells that …