004586 B6.Cg-Tg (Vil1-cre)997Gum/J These Vil1-cre mice express Cre recombinase in villus and crypt epithelial cells of the small and large intestines and may be useful in studies of intestinal organogenesis.

Many workgroups used Villin-Cre transgenes to restrict recombination of floxP -flanked genes to the epithelial cells of the small and large intestines either with a constitutive expression (Vil-Cre) or with a tamoxifen-inducible expression (Vil-Cre-ER T2) [118].

Substances Microfilament Proteins Vil1 protein, mouse Cre recombinase Integrases

020282 B6.Cg-Tg (Vil1-cre/ERT2)23Syr/J vil-Cre-ER^T2 mice carry a transgene with tamoxifen inducible Cre recombinase under the control of the 9 kb mouse <em>Vil1</em>, villin 1, promoter, and may be useful for generating specific targeted mutants for studies of the crypt-villus axis of the intestinal epithelium.

033019 B6N.Cg-Tg (Vil1-cre)20Syr/J Mice harboring the vil-Cre transgene have the 9-kb mouse, <em>Vil1</em>, villin 1, promoter directing expression of Cre recombinase to the intestinal epithelia and kidney, and may be useful for generating conditional mutations in cells of the crypt villus axis and kidney.

We generated two complementary systems for Cre-mediated recombination of target genes in the mouse digestive epithelium and tested them with a Cre-reporter mouse strain. Cre was expressed under the control of a 9 kb regulatory region of the murine villin gene (vil-Cre).

Summary: We generated two complementary systems for Cre-mediated recombination of target genes in the mouse digestive epithelium and tested them with a Cre-reporter mouse strain. Cre was expressed under the control of a 9 kb regulatory region of the murine villin gene (vil-Cre).

Villin-Cre Apcfl/+ KRasG12D/+ Mouse: conditionally expressed an oncogenic K-rasD12 allele in the small intestine of adult mice either alone or in the context of Apc deficiency.

Jul 13, 2004 · We generated two complementary systems for Cre-mediated recombination of target genes in the mouse digestive epithelium and tested them with a Cre-reporter mouse strain. Cre was expressed under the control of a 9 kb regulatory region of the murine villin gene (vil-Cre).

Oct 21, 2020 · Villin is an actin-binding protein that is encoded by Vil1. The transgenic mice in which Vil1 acts as a promoter of Cre are widely used to inactivate the intestinal epithelium's genes.