035670 B6.Cg-Tg(VAV1-cre)1Graf/MdfJ Vav-Cre transgenic mice express Cre recombinase under the control of the human vav 1 oncogene ( VAV1 ) regulatory elements in all nucleated …

Cre transgenic mice can be used to delete gene sequences flanked by loxP sites in specific somatic tissues. We have generated vavCre transgenic mice, which can be used to inactivate …

008610 B6.Cg- Commd10 Tg(Vav1-icre)A2Kio /J Vav-iCre transgenic mice have the mouse HS21/45 control regions directing expression of an optimized variant of Cre recombinase …

Nov 7, 2013 · Vav-Cre. Vav is a guanine nucleotide exchange factor regulated by the Rho/Rac family of small G proteins (Lazer and Katzav, 2011). The constitutively active Vav-Cre mice …

This strain carries a mouse Vav1 gene promoter-driven improved Cre (iCre) expression element insertion. When H11-Alb-iCre mice are crossed with mice containing loxP sites, Cre …

We have generated mouse lines expressing Cre recombinase in hematopoietic tissues using the vav regulatory elements, or in lymphoid cells using the hCD2 promoter and locus control …

Jan 1, 2003 · We have generated vavCre transgenic mice, which can be used to inactivate genes specifically in adult hematopoietic and endothelial cells. In these animals, a Cre transgene is …

Nov 7, 2002 · We have generated vavCre transgenic mice, which can be used to inactivate genes specifically in adult hematopoietic and endothelial cells. In these animals, a Cre transgene is …

Vav-iCre expresses active Cre in fetal and adult hematopoietic stem cells and all descendants, hCD2-iCre in immature and mature B and T lymphocytes. To better characterize which …

5 days ago · To overcome these limitations, we generated a hematopoietic-specific Gba knockout model by crossing Gba fl/fl mice with Vav-Cre, enabling early deletion of Gba exons 8–11 in …