A combination of blood tests is needed to diagnose von Willebrand disease (VWD). The following screening tests are done first to show if the blood is clotting properly. These tests may suggest a possible bleeding disorder, but more tests are needed to tell the type of bleeding disorder present.

Laboratory diagnosis requires a series of assays of von Willebrand factor (VWF) quantity and function, and factor VIII activity, with no single straightforward diagnostic test available to either confirm or exclude the diagnosis.

Oct 26, 2021 · To evaluate you for von Willebrand disease, your doctor will likely ask you detailed questions about your medical history and check for bruises or other signs of recent bleeding. Your doctor will also likely recommend the following blood tests: Von Willebrand factor antigen.

Dec 1, 2009 · Von Willebrand disease is an inherited condition characterized by deficiency of von Willebrand factor, which is essential in hemostasis. The National Heart, Lung, and Blood Institute has...

Dec 22, 2018 · Von Willebrand factor (VWF) testing is used to investigate excessive or recurrent bleeding episodes or a personal or family history of excessive bleeding. Testing is used to help diagnose von Willebrand disease (VWD) and distinguish between the various types of VWD.

Jan 16, 2025 · Separate topic reviews discuss the treatment and pathophysiology of VWD, the diagnosis and treatment of acquired von Willebrand syndrome (AVWS), and a general approach to bleeding disorders.

Some of the blood tests used to diagnose VWD are: von Willebrand Factor Antigen – This test measures how much VWF is in the blood. It does not tell how well the VWF functions. Ristocetin Cofactor Assay – Normal platelets and the antibiotic ristocetin are added to the tube of plasma from the person being tested.

In this review, we highlight the current status of clinical testing and diagnostic classifications that are useful to the clinician while also underscoring the current limitations of the existing tests.

Detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity. Subtyping von Willebrand disease (VWD) as type 1 (most common), type 2 variants (less common), or type 3 (rare) This test is …

A workup for von Willebrand disease (VWD) initially involves evaluation of von Willebrand factor (VWF) quantity and function and factor VIII (FVIII) activity. Specific laboratory tests include VWF antigen, VWF ristocetin cofactor (VWF:RCo) activity …