Von Willebrand factor (VWF) is a plasma glycoprotein that acts as carrier for factor VIII. Elevated levels of VWF are associated with elevated coagulation factor VIII levels. An increased VWF level in plasma is found to be associated with VTE [4, 5, 11, 13].

Sep 21, 2006 · Results— vWF antigen and activity levels were significantly higher in cases than in controls. The relative risk of ischemic stroke was highest in individuals in the upper quartile of vWF:Ag (odds ratio, 3.2; 95% CI, 1.4 to 7.5) and vWF:RCo (odds ratio, 2.1; 95% CI, 0.9 to 4.8) compared with individuals in the lowest quartiles.

Dec 1, 2009 · Von Willebrand disease is an inherited condition characterized by deficiency of von Willebrand factor, which is essential in hemostasis. The National Heart, Lung, and Blood Institute has...

Dec 22, 2018 · Von Willebrand factor (VWF) testing is used to investigate excessive or recurrent bleeding episodes or a personal or family history of excessive bleeding. Testing is used to help diagnose von Willebrand disease (VWD) and distinguish between the various types of VWD.

Dec 30, 2021 · von Willebrand disease (VWD) is associated with significant morbidity as a result of excessive mucocutaneous bleeding. Early diagnosis and treatment are important to prevent and treat these symptoms.

Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes primary hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura , Heyde's syndrome , and possibly hemolytic ...

Oct 26, 2021 · To evaluate you for von Willebrand disease, your doctor will likely ask you detailed questions about your medical history and check for bruises or other signs of recent bleeding. Your doctor will also likely recommend the following blood tests: Von Willebrand factor antigen.

What does it mean if your Von Willebrand Factor Antigen (vWF) result is too high? Increased concentrations of VWF antigen and VWF activity are not considered diagnostic. VWF is one of many acute phase reactants.

Jan 7, 2021 · High VWF plasma levels are associated with increased risk of venous thromboembolism. The association is strongest for unprovoked events. Several case-control studies have reported elevated plasma von Willebrand factor (VWF) levels in patients with venous thromboembolism (VTE) compared with controls.

Aug 1, 2024 · Von Willebrand factor (VWF) is a protein crucial to the blood clotting process. If you don’t have enough of this protein, or if it doesn’t work as it’s supposed to, you may have von...