We identified a novel NFAT target, caspase-8 inhibitor cellular Fas-associated death domain–like interleukin 1β–converting enzyme inhibitory protein (c-FLIP), whose expression was …

Background: VEGF-calcineurin-nuclear factor of activated T cells (NFAT) signaling regulates endothelial cell homeostasis. Results: Novel NFAT targets were identified by genome-wide …

Oct 17, 2014 · Here we performed comprehensive mapping of genome-wide NFATc1 binding in VEGF-stimulated primary cultured endothelial cells and elucidated the functional …

Apr 19, 2002 · VEGF was found to be overexpressed about 3- to 4-fold higher in the somites, which are avoided by early vessels, indicating that NFAT signaling suppresses genes that …

Jul 27, 2016 · This paper describes how VEGF–VEGFR2 on an endothelial cell can bind to NRP1 on an adjacent cell (that is, trans-binding), regulating VEGFR2 endocytosis, tumour initiation …

Another gene upregulated by VEGF predominantly via NFAT, which is not induced by EGF, is the DSCR-1 gene. The calcineurin inhibitor DSCR-1 seems to be induced by VEGF in a negative …

Jun 5, 2016 · In this study we developed a new RGA based on the VEGF-VEGFR2-NFAT pathway, a main mechanism of action of VEGF. Several distinct isoforms of VEGF-A exist as a …

The results indicate that VEGF treatment promotes the proliferative capacity of human EPCs by activating CaN/NFAT signalling leading to increased eNOS protein expression and NO …

The VEGF Bioassay is a bioluminescent cell-based assay that measures VEGF stimulation and inhibition of KDR (VEGFR2) using the NFAT-RE as a readout.

Another gene upregulated by VEGF predominantly via NFAT, which is not induced by EGF, is the DSCR-1 gene. The calcineurin inhibitor DSCR-1 seems to be induced by VEGF in a negative …