Unc-51-like kinase 2 (C. elegans) also known as ULK2 is an enzyme which in humans is encoded by the ULK2 gene. [1] The gene is located within the Smith–Magenis syndrome region on …

Mar 30, 2025 · ULK2 (Unc-51 Like Autophagy Activating Kinase 2) is a Protein Coding gene. Diseases associated with ULK2 include Frontotemporal Dementia And/Or Amyotrophic Lateral …

Oct 24, 2011 · In addition, ulk2 −/− murine embryonic fibroblasts (MEFs) have been reported to display normal autophagy induction after starvation in HBSS, and only the additional …

Altogether, our results indicate that skeletal muscle ULK2 has a unique role in basal selective protein degradation by stimulating the recognition and proteolytic sequestration of insoluble …

Jul 2, 2020 · To understand the differences between ULK1 and ULK2, we compared the human ULK1 and ULK2 proteins and their regulation.

ULK2 Is a Key Pro-Autophagy Protein That Contributes to the High Chemoresistance and Disease Relapse in FLT3-Mutated Acute Myeloid Leukemia. An ULK1/2-PXN …

Ulk1 and Ulk2 are important for MTORC1 inhibition-induced autophagy in preadipocytes. In order to understand how Ulk1 and Ulk2 affect basal and rapamycin-induced autophagy in 3T3-L1 …

Uncoordinated 51-like kinase 2 (ULK2), a member of the serine/threonine kinase family, plays an essential role in the regulation of autophagy in mammalian cells. Given the role of autophagy …

One of the hypermethylated genes in GBM, ULK2, an upstream autophagy inducer, was found to be down-regulated in GBM. Promoter hypermethylation of ULK2 was confirmed by bisulfite …

Aug 9, 2019 · To overcome a potential limitation in the sensitivity of these antibodies, we cotransfected (via electroporation) a full-length wild-type Ulk2 construct containing sequential …