Jun 19, 2024 · This helps radiologists to determine the certainty of usual interstitial pneumonia (UIP) diagnosis based on HRCT chest findings. The importance of this guideline is that (definite) UIP pattern on chest HRCT precludes the need for tissue diagnosis 1,2,5 .

UIP may be diagnosed by a radiologist using computed tomography (CT) scan of the chest, or by a pathologist using tissue obtained by a lung biopsy. Radiologically, the main feature required for a confident diagnosis of UIP is honeycomb change in the periphery and the lower portions (bases) of the lungs. [3]

For patients with newly detected ILD of apparently unknown cause who are clinically suspected of having IPF and have an HRCT pattern of probable UIP, indeterminate for UIP, or an alternative diagnosis, we suggest SLB (conditional recommendation, very low quality of evidence).

Oct 14, 2024 · The histological diagnosis of UIP is based on temporal and spatial heterogeneity, the identification of fibrotic lesions at different stages (fibroblastic infiltrates, mature fibrosis, and honeycombing) within the same biopsy specimen and architectural distortion.

According to current international guidelines, HRCT plays a key role in establishing a diagnosis of usual interstitial pneumonia (UIP). Current guidelines describe three UIP patterns based on HRCT findings: a typical UIP pattern; a pattern designated “possible UIP”; and a pattern designated “inconsistent with UIP”, each pattern having ...

Feb 28, 2022 · This editorial focuses on common issues that surround the diagnosis of usual interstitial pneumonia (UIP), a clinically significant pathologic diagnosis.

Jun 19, 2024 · The 2018 revised diagnostic HRCT criteria for usual interstitial pneumonia (UIP) pattern published by the American Thoracic Society, the European Respiratory Society, the Japanese Respiratory Society, and the Latin American Thoracic Association has converged to a similar categorization of the HRCT findings into four groups.

Histopathology Demonstrating Usual Interstitial Pneumonia (UIP) Diagnostic Algorithm for Idiopathic Pulmonary Fibrosis (IPF) Natural History of IPF. Idiopathic Pulmonary Fibrosis: Rate of FVC Decline/Disease Progression . All information in this pocket guide is derived from the 2011, 2015 and 2018 IPF guidelines unless otherwise noted.

Sep 12, 2018 · Eight pathologically defined interstitial pneumonias are included in a newly revised classification system, published in the American Journal of Respiratory and Critical Care Medicine in 2013. Suspected PPFE in a 73-year-old female with progressive dyspnea and hypoxemia.

The American Thoracic Society guidelines for the diagnosis of UIP pattern break down CT findings into four categories: UIP, probable UIP, indeterminate for UIP, and alternative diagnosis.