OCT: OCT demonstrates (Figure 1C, arrow) irregular RPE elevation in contrast to the smooth elevation of a serous PED, with heterogenous features often along the back surface of the detached RPE. Scant overlying subretinal fluid may sometimes be seen.

Jan 1, 2025 · PED in OCT is diagnosed through imaging techniques such as optical coherence tomography (OCT) and fluorescein angiography. These tests allow ophthalmologists to visualize the detachment of the retinal pigment epithelium (RPE) from the underlying Bruch’s membrane.

In the clinically diagnosed PED patients, diagnosis can be confirmed with optical coherence tomography (OCT), which is an easy and noninvasive method to examine subpigment epithelial fluid and concomitant drusen, intraretinal fluid, and other findings.

On OCT imaging, a PED is identified when a space is formed between the RPE and Bruch’s membrane. This space can be filled with a moderately hyper-reflective material in a druesnoid PED or show mixed hyper- and hypo-reflectivity consistent with the vascular and exudative component of a CNV in a fibrovascular or serous PED.

Oct 8, 2022 · In the present case, OCT showed clear fluid in a later stage of the patient’s trajectory (Figure 6). Earlier, however, the PED could have been interpreted as being turbid (Figure 4). This apparent dilemma can be resolved by reconciling the clinical appearance manifesting pigment with the OCT.

Jan 5, 2017 · Pigmentary changes overlying the PED can appear as intraretinal hyperreflective material on OCT. Recent studies show that disruptions in the RPE hyperreflective band preceded the collapse and change in PED volume that most commonly results in RPE atrophy.

Dec 1, 2018 · OCTA can be used to distinguish vascular PEDs from non-neovascular PEDs, assisting in disease diagnosis. 18 Non-neovascular PEDs, including drusenoid and serous PEDs, have no flow signal within or adjacent to the lesion and …

This is an OCT of a pigment epithelial detachment (PED) in wet AMD with some adjacent subretinal fluid (SRF) and an overlying area of focal intraretinal fluid (IRF). Drusen: Lumps of deposits under the RPE.

The OCT findings of an associated serous PED typically show a well-circumscribed convex, dome-shaped outpouching of the RPE with a smooth surface, steep edges, and a homogenous underlying hyporeflective space . Less commonly, a hyperreflective appearance under the RPE may be associated with more turbid exudation or fibrin.

Serous PED may be imaged by fluorescein angiography (FA), indocyanine green angiography (ICGA) and optical coherence tomography (OCT). FA represents, however, the gold standard for diagnosis of serous PED.