The trophoblast (from Greek trephein: to feed; and blastos: germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. [ 1 ] They provide nutrients to the embryo and develop into a large part of the placenta .

5 days ago · A useful component of current placentation and trophoblast research are a number of trophoblast cell lines that have been derived from a number of different sources including term placenta, choriocarcinomas and transformation of primary isolated cells.

Trophoblast Function. Trophoblasts play an important role in embryo implantation and interaction with the endometrium of the maternal uterus following decidualization. The trophoblast is composed of two layers: an inner cytotrophoblast and an outer syncytiotrophoblast.

Oct 30, 2023 · Trophoblast Trophoblast Cells lining the outside of the blastocyst. After binding to the endometrium, trophoblasts develop into two distinct layers, an inner layer of mononuclear cytotrophoblasts and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblasts, which form the early fetal-maternal interface (placenta).

The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two-layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the ...

The blastomere cells in the blastocyst are arranged into an outer layer called the trophoblast. The inner cells of the trophoblast are termed inner cell mass. Later, the trophoblast gets attached to the endometrium of the uterus.

…cells; these cells are the trophoblast, which has a special ability to attach to and invade the uterine wall. The trophoblast plays an important role later in the development of the placenta or afterbirth.

Jun 5, 2022 · This review article focuses on what is known about very early processes in human reproduction and emphasizes on morphological and functional aspects of early trophoblast differentiation and subpopulations.

Oct 20, 2005 · Trophoblast invasion and migration through the uterine wall is mediated by molecular and cellular interactions, controlled by the trophoblast and the maternal microenvironment. This review is focused on the molecular constituents of the human trophoblast, their actions and interactions, including interrelations with the uterine endometrium.

The trophoblast cells of the embryonic pole differentiate and multiply and form the invasive syncytio- trophoblast. The abembryonic pole consists of cytotrophoblast cells.