A triazole is a heterocyclic compound featuring a five-membered ring of two carbon atoms and three nitrogen atoms with molecular formula C 2 H 3 N 3. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring.

Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole.

May 3, 2024 · Triazole demonstrates distinctive physicochemical properties, characterized by weak basicity, various dipole moments, and significant dual hydrogen bond acceptor and donor capabilities. These features are poised to play a pivotal role in drug–target interactions.

Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole.

Triazole derivatives are showing very promising and excellent therapeutic effectiveness. The major activities exhibited by these derivatives include insecticidal, antifungal, antiviral, antibacterial, sedative, hypnotic, anticonvulsant and anti-inflammatory action.

Triazole is an important class of heterocyclic compounds exhibiting a wide range of pharmacological activities. It is also known as pyrrodiazoles, and is a five-membered, diunsaturated ring system containing three nitrogen atoms in a heterocyclic core and occurs in two possible isomeric forms, 1,2,3 triazoles and 1,2,4 triazoles (Fig. 9.1).

Apr 22, 2024 · What are pyrazoles, triazoles and tetrazoles? Derivatives of pyrazoles, triazoles and tetrazoles are stable aromatic compounds. Many of them have been used as pharmaceuticals, dyes and pesticides. The tetrazoles are relevant in medicinal chemistry. This is because the tetrazole group behaves similar to carboxylic acids.

Triazole derivatives are used as biologically active substances of various actions, have antibacterial, antipsychotic, hypotensive and antispasmodic activity, stimulate cardiac activity.

Apr 25, 2022 · Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole.

Apr 5, 2025 · The meaning of TRIAZOLE is any of a group of compounds that are characterized by a ring composed of two carbon atoms and three nitrogen atoms and that include a number of antifungal agents (as fluconazole).