Triggering receptor expressed on myeloid cells 1 (TREM1) is an immunoglobulin (Ig) superfamily transmembrane protein that, in humans, is encoded by the TREM1 gene. [5][6][7] TREM1 is …

Feb 7, 2023 · In this Review, I detail the genomic organization, structure and signalling mechanisms of TREMs, and extensively discuss the functions of TREM1 and TREM2, which …

Mar 30, 2025 · TREM1 (Triggering Receptor Expressed On Myeloid Cells 1) is a Protein Coding gene. Diseases associated with TREM1 include Maxillary Sinusitis and Pneumonia. Among its …

Triggering receptors expressed on myeloid cells (TREMs) are a family of cell-surface receptors expressed broadly on myeloid cells. The first TREM identified, TREM1, was characterized as …

TREM-1 is an important signaling receptor expressed on neutrophils and monocytes that plays an important role in systemic infections. Here, we review the intracellular signaling pathways that …

Triggering receptor expressed on myeloid cells 1 (TREM-1) plays a pivotal role in human health and disease (1 – 6). Despite promising preclinical data and safety in humans, the first clinical …

Triggering receptor expressed on myeloid cells-1 (TREM-1) is an immune receptor expressed by myeloid cells that has the capacity to augment pro-inflammatory responses in the context of a …

Feb 19, 2025 · Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages. Molecular and immunological …

Jun 1, 2024 · In this review, we aimed to convey insights into the role of TREM1 signaling in cancer and emphasize its potential value as a diagnostic marker and therapeutic target. We …

Jul 19, 2021 · TREM-1 (triggering receptor expressed on myeloid cells-1) is a transmembrane receptor expressed by innate immune cells, including endothelial cells and platelets.