Oct 2, 2024 · The thyrotropin receptor antibody (TRAb) test is a blood test that helps healthcare providers diagnose the autoimmune thyroid condition called Graves' Disease. The antibodies it tests for are present in between 90% and 100% of the people who have this disease.

Feb 12, 2025 · What is a thyroid antibody test? A thyroid antibody test is a blood test that can help find the cause of low or high thyroid hormone levels. More specifically, it can check if you have an autoimmune thyroid disease — either Hashimoto’s disease or Graves’ disease.

TRAb (TSH Receptor Binding Antibody) - Measurement of TRAb is used to diagnose and manage Graves' disease, neonatal hypothyroidism, and postpartum thyroid dysfunction. TRAb, which measures the ability of antibodies to inhibit TSH binding to its receptor, reflects the presence of either or both the stimulatory and inhibitory immunoglobulin classes.

Thyrotropin-receptor antibody is an autoantibody to the thyroid cell receptor for thyroid-stimulating hormone. It can be demonstrated in 90% of patients with Graves' disease, and is the cause of the hyperthyroidism of that condition.

What are thyroid stimulating antibodies (TRAb) and why is it tested? In Graves’ disease, the thyroid stimulating antibodies (TRAb) mimic the thyroid stimulating hormone (TSH) secreted by the pituitary gland.

The sensitivity and specificity of an elevated thyrotropin receptor antibody (TRAb) test for Graves disease (GD) diagnosis depends on whether patients have disease treated with antithyroid drugs or clinically active, untreated disease.

Recommended first-line test for detection of thyrotropin receptor antibodies. The following situations: -Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans.

TSH receptor antibody (TRAb) is considered the gold standard diagnostic test for the autoimmunity of Graves’ disease (GD), which is commonly diagnosed clinically. To evaluate the true positive (sensitivity) and true negative (specificity) rates of clinical diagnosis of GD or non-GD hyperthyroidism compared to the TRAb test.

The test is the recommended first-line test for detection of thyrotropin receptor antibodies and measures the presence of stimulating, blocking and neutral antibodies. Using a decision limit of 1.75 IU/L, the test has a sensitivity of 97% and a specificity of 99% for …

Acceptable secondary test for autoimmune thyroid disease. ||Allow serum separator to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum from cells ASAP or within 2 hours of collection.