Pulmonary hypoplasia is another typical manifestation in CDH that can be assessed by lung volume and size measurements. However, LHR and TFLV are quantitative evaluation predictors that cannot offer information about fetal lung maturity.

Objective: The purpose of this study was to evaluate observed/expected (O/E) lung-to-head ratio (LHR) by ultrasound (US) and total fetal lung volume (TFLV) by magnetic resonance imaging as neonatal outcome predictors in isolated fetal congenital diaphragmatic hernia (CDH).

lung volume (TFLV) by magnetic resonance imaging as neonatal out-come predictors in isolated fetal congenital diaphragmatic hernia (CDH). STUDYDESIGN: Weconductedaretrospectivestudyof72fetuseswith isolated CDH, in whom O/E LHR and TFLV were evaluated as survival predictors. RESULTS: O/ELHRonUSandO/ETFLVbymagneticresonanceimag-

Observed-to-expected total fetal lung volume (o/e TFLV) has been shown to be a predictor of severity and useful in risk stratification but is variable due to different TFLV formulas. Objectives: To calculate o/e TFLV for CDH patients part of a twin gestation using the unaffected sibling as an internal control and comparing these values to those ...

To evaluate observed/expected (o/e) lung head ratio (LHR) by US and o/e total fetal lung volume (TFLV) by MRI as predictors of neonatal survival in prenatally diagnosed isolated CDH in a high volume centre.

Nov 2, 2024 · MRI allows the measurement of fetal lung volumes which provide an estimate of the severity of pulmonary hypoplasia. The total fetal lung volume (TFLV) can be calculated from a contiguous T2-weighted HASTE sequence and an observed-to-expected TFLV (O/E …

Sep 9, 2024 · Severe CDH was defined if O/E TFLV was <32% and liver herniation >21%. Prediction of survival was evaluated using ROC and their areas under the curves (AUCs) and logistic regression analyses adjusting by CDH severity and liver herniation.

Oct 12, 2020 · This study demonstrates that segmentation of the fetal lungs using a free software (3DSlicer) is an adequate tool to evaluate TFLV in cases of severe CDH and correlates well with the TFLV assessed by conventional methods, a known predictor for neonatal survival . Our results revealed good correlation between two different techniques to evaluate ...

This study aimed to evaluate whether GA determined by first-trimester dating or fetal size at imaging affects the ability of O/E-TFLV to predict 6-month survival in fetuses with isolated left-sided CDH.

Sep 18, 2024 · Data from the international Tracheal Occlusion to Accelerate Lung Growth (TOTAL) trials, have demonstrated the efficacy of fetal endoscopic tracheal occlusion (FETO) in severe left CDH (LCDH).