Jun 30, 2023 · We show here that over-expression of E2F1 and forced inactivation of pRB, by adenovirus E1a, induced TFDP1 gene expression in human normal fibroblast HFFs, …

Mar 30, 2025 · TFDP1 (Transcription Factor Dp-1) is a Protein Coding gene. Diseases associated with TFDP1 include Hepatocellular Carcinoma and Colorectal Cancer. Among its related …

The E2F transcription factor family (see MIM 189971) regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as …

Feb 15, 2024 · These results collectively suggest that TFDP1 and E2F proteins cooperatively regulate chromatin accessibility. TFDP1 modulates the accessibility via histone transcription

Jun 30, 2023 · To explore whether serum induction of TFDP1 gene expression is mediated through E2F, we examined kinetics of TFDP1 gene expression after serum stimulation and …

Jul 23, 2024 · Using this experimental system, we identified the TFDP1 transcription factor to be essential for HSPC proliferation and post-transplant hematopoiesis. We further discovered that …

Nov 15, 2003 · We determined expression levels of TFDP1 and E2F1 in 41 primary HCCs by means of quantitative real-time reverse transcription-polymerase chain reactions, and looked …

This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes.

Jun 30, 2023 · In this study, we found that TFDP1 gene expression is induced by serum stimulation of human normal fibroblasts and also by forced activation of E2F, by over …

Expression levels of TFDP1 and E2F1 correlated with those of seven transcriptional targets ( TYMS, DHFR, PCNA, RRM1, CCNE1, CDC2, and MYBL2) that play important roles in the …