Tetracycline-controlled transcriptional activation is a method of inducible gene expression where transcription is reversibly turned on or off in the presence of the antibiotic tetracycline or one of …

The Tet-controlled transactivator, Tet-Off Advanced, is a fusion protein derived from the E. coli Tet repressor protein, TetR, which is joined to three minimal transcription activation domains from …

The initial system Gossen and Bujard developed is known as tetracycline off: in the presence of tetracycline, expression from a tet-inducible promoter is reduced.

Tet-On and Tet-Off brands are the highest-performing and most-cited inducible mammalian expression systems. Since the orignal first generation of Tet-On and Tet-Off Systems a series …

Apr 1, 2015 · The Tet-Off and Tet-On expression systems are binary transgenic systems in which expression from a target transgene is dependent on the activity of an inducible transcriptional …

Tet-Off cell lines are host cell lines that greatly simplify the task of setting up a tetracycline-inducible gene expression system that is activated by removing doxycycline (Dox) from the …

The Tet-Off system allows silencing of gene expression by administration of tetracycline (Tc) or tetracycline-derivatives like doxycycline (dox), whereas the Tet-On system allows activation of …

Jan 14, 2020 · In the presence of tetracycline, tTA is unable to bind to the TetO and expression of the gene is turned off (hence the name “Tet-Off”). In an opposite manner, the “Tet-On” system …

In this study, we investigated whether an inducible Tetracycline (Tet)-Off system with β-cell–specific mouse insulin promoter (MIP)-itTA–driven expression of tetracycline operon …

一个TRE是一个19个核苷酸的 四环素操作符 (tetO)序列的7个重复，被 四环素抑制因子 (tetR)识别。 在内源性细菌系统中，如果四环素或其类似物之一如强力霉素存在，tetR将与四环素结合而 …