Transcription factor 7 (TCF7) plays an essential role in Wnt signaling by interacting with β-catenin. Emerging evidence demonstrates that overexpression of TCF7 promotes progression or correlates with poor progression in several types of cancers, ...

Mar 1, 2025 · TCF7 is a critical transcription factor promoting BC progression. High TCF7 expression in BC is significantly linked to poor patient prognosis. We uncovered a novel mechanism by which TCF7 drives EMT and stemness in BC through transcriptional regulation of TGFBR1, impacting the TGF-β/SMAD3 pathway.

We used immunohistochemistry (IHC) to analyze the relationship between TLSs and prognosis. Multiplex immunohistochemistry (MIHC), flow cytometry (FCM) and spatial analysis were performed to verify the characteristics of TCF1/TCF7 + T cells.

Aug 1, 2021 · We used immunohistochemistry (IHC) to analyze the relationship between TLSs and prognosis. Multiplex immunohistochemistry (MIHC), flow cytometry (FCM) and spatial analysis were performed to verify the characteristics of TCF1/TCF7+ T cells.

Find the TCF7 antibody that fits your needs. Choose from 1 of 20 TCF7 antibodies, which have been validated in experiments with 20 publications and 49 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with...

We analyzed publicly available ATAC-seq and ChIP-seq datasets, together with genomic deletions using CRISPR/Cas9 technology, to identify regulatory regions controlling Tcf7 expression in early stages of T cells and ILC development.

14464-1-AP targets TCF1/TCF7 in WB, IHC, IF-P, IP, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at …

Apr 15, 2022 · WNT3A-TCF7-SOX9 axis could induce pemigatinib resistance in two independent pathways: (1)SOX9 directly promotes FGFR2 transcription and expression; (2)SOX9 elevates FGF7 expression, which...

Mar 30, 2025 · TCF7 (Transcription Factor 7) is a Protein Coding gene. Diseases associated with TCF7 include Gastric Cardia Adenocarcinoma and Lung Cancer. Among its related pathways are Autodegradation of the E3 ubiquitin ligase COP1 and ncRNAs involved in Wnt signaling in hepatocellular carcinoma.

TCF1/TCF7 (C63D9) Rabbit mAb detects endogenous levels of total TCF1/TCF7 protein. This antibody does not recognize the dominant negative isoforms of TCF1/TCF7 lacking the amino-terminal β-catenin binding domain and does not cross-react with LEF1.