Transporter associated with antigen processing 1 (TAP1) is a protein that in humans is encoded by the TAP1 gene. A member of the ATP-binding cassette transporter family, it is also known as ABCB2. [5] [6]

Mar 30, 2025 · TAP1 (Transporter 1, ATP Binding Cassette Subfamily B Member) is a Protein Coding gene. Diseases associated with TAP1 include Mhc Class I Deficiency 1 and Mhc Class I Deficiency. Among its related pathways are Antigen processing-Cross presentation and Class I MHC mediated antigen processing and presentation.

The TAP1 gene provides instructions for making a protein that plays an important role in the immune system. The TAP1 protein assembles with another protein called TAP2 (produced from the TAP2 gene) to form a protein complex called transporter associated with …

Transporter associated with antigen processing 1 (TAP1) is a transporter protein that represent tumor antigen in the MHC I or HLA complex. Any defect in the TAP1 gene resulting in inadequate tumor tracking. TAP1 influences multidrug resistance (MDR) in human cancer cell lines and hinders the treatme …

Yeast protein Mex67p and human NXF1, also-called TAP, are the two best-characterized NXFs (nuclear transport factors).

Transporter associated with antigen processing 1 (TAP1) is a transporter protein that represent tumor antigen in the MHC I or HLA complex. Any defect in the TAP1 gene resulting in inadequate tumor tracking. TAP1 influences multidrug resistance (MDR) ...

TAP is a heterodimer and consists of two subunits, TAP1 and TAP2, which are encoded in the class II region of the HLA locus on chromosome 6. Deletion or mutation of either or both TAP1 and TAP2 proteins severely impairs the translocation of peptides into the ER.

Traditionally, the transporter associated with antigen processing type 1 (TAP1) is critical for antigen presentation to regulate adaptive immunity. However, its role in controlling viral infections through modulating innate immune signaling is not yet fully understood.

TAP1, a potential immune-related prognosis biomarker with functional significance in uveal melanoma. Antigen Peptide Transporter 1 (TAP1) Promotes Resistance to MEK Inhibitors in Pancreatic Cancers. Association study of TAP and HLA-I gene combination with chronic hepatitis C virus infection in a Han population in China.

Feb 11, 2023 · TAP1 is an immunomodulation-related protein that plays different roles in various malignancies. This study investigated the transcriptional expression profile of TAP1 in uveal melanoma (UVM), revealed its potential biological interaction network, and determined its prognostic value.