May 6, 2021 · Thrombotic thrombocytopenic purpura (TTP) remains an important hematologic emergency that must be promptly recognized. This chapter attempts to disentangle these …

Sep 24, 2024 · Thrombotic microangiopathy involves tiny clots forming within the microvasculature. This leads to erythrocyte fragmentation (which is termed MAHA: …

Sep 21, 2024 · Thrombocytopenia (<150,000 platelets) is extremely common in the ICU. It is often a poor prognostic sign that is associated with systemic inflammation. Most cases of …

Thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are multisystemic disorders that are characterized by thrombocytopenia, microangiopathic …

Thrombotic thrombocytopenic purpura (TTP) is fatal in 90% of patients if left untreated and must be diagnosed early to optimize patient outcomes.

TTP is a rare, life-threatening thrombotic microangiopathy or blood disorder. In TTP, blood clots form in small blood vessels throughout the body and can limit or block the flow of oxygen-rich …

Mar 27, 2021 · This patient has thrombotic thrombocytopenic purpura (TTP), a rare but deadly disease with an untreated mortality approaching 100%. TTP involves microangiopathic …

Thrombotic microangiopathies are a group of disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia and microthrombi leading to ischemic tissue injury. 1 …

Thrombotic microangiopathies (TMAs) comprise a heterogeneous set of conditions linked by a common histopathologic finding of endothelial damage resulting in microvascular thromboses …

Apr 7, 2025 · The Internet Book of Critical Care is an online textbook written by Josh Farkas (@PulmCrit), an associate professor of Pulmonary and Critical Care Medicine at the University …