Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. [9] It is the principal psychoactive constituent of Cannabis and one of at least 113 total cannabinoids identified on the plant.

In this work, we investigated the combination of Ag (I) ions and PS-MS for the rapid and selective analysis of THC and CBD, in particular for detecting low concentrations of THC in CBD oils.

Two marijuana compounds of particular medical interest are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). A gas chromatography–tandem mass spectrometry (GC–MS-MS) method was developed to test for CBD, THC, hydroxy-THC (OH-THC) and carboxy-THC (COOH-THC) in …

In this review, we outline the known interactions of CBD and other cannabinoids on molecular targets, particularly voltage-gated sodium channels (Na v), and discuss potential mechanisms of CBD besides the known interactions with CB1 and CB2.

May 28, 2024 · This study explores the use of Ag-ligand ion complexation and electrospray ionization tandem mass spectrometry (ESI-MS/MS) for the differentiation of Δ 9-THC and CBD using six different Ag complexes.

Mar 8, 2022 · Among the abundance of cannabinoids identified in cannabis, the active parent drug, Δ 9 -tetrahydrocannabinol (Δ 9 -THC), and its oxidized metabolite, 11-nor-9-carboxy-Δ 9 -THC (Δ 9 -THCCOOH), are attractive analytical targets to detect cannabis use. More recently, confirmation of these analytes may be hindered by a related interfering compound.

Jan 8, 2025 · Tetrahydrocannabinol (THC) is the principal psychoactive compound derived from the cannabis plant Cannabis sativa and approved for emetic conditions, appetite stimulation and sleep apnea relief....

Dec 3, 2020 · Quantitative analysis of Δ 9 -tetrahydrocannabinol (Δ 9 -THC) in oral fluid has gained increasing interest in clinical and forensic toxicology laboratories. New medicinal and/or recreational cannabinoid products require laboratories to distinguish different patterns of cannabinoid use.

Dec 1, 2024 · Silver-phosphine ion complexation can be used to identify marijuana. ∆ 9 -THC, CBD, ∆ 9 -THCA, and CBDA are differentiated using unique MS/MS product ions. Characterization of the fragmentation patterns for 10 common cannabinoids. 18/20 authentic samples were correctly identified as marijuana or not marijuana.

In this review, we will outline the studies that report reproducible results of CBD and other cannabi-noids changing membrane channel function, with particular interest on Nav. Nav are implicated in fatal forms of epilepsy and are also associated with chronic pain.