Transforming growth factor, beta receptor II (70/80kDa) is a TGF beta receptor. TGFBR2 is its human gene. It is a tumor suppressor gene. [5] This gene encodes a member of the …

Mar 30, 2025 · TGFBR2 (Transforming Growth Factor Beta Receptor 2) is a Protein Coding gene. Diseases associated with TGFBR2 include Loeys-Dietz Syndrome 2 and Esophageal Cancer. …

The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell …

TGFBR2 forms an endocytic complex with PTH1R in response to PTH and regulates signalling by PTH and TGF-beta. TGFBR2 directly phosphorylates the PTH1R cytoplasmic domain, which …

Mar 24, 2025 · TGFBR2 is a constitutively active serine/threonine kinase receptor that binds TGF-β ligands and phosphorylates TGFBR1, initiating intracellular signaling. Unlike TGFBR1, which …

Sep 8, 2024 · Go to complete Gene record for TGFBR2; Go to Variation Viewer for TGFBR2 variants; Summary. The protein encoded by this gene is a transmembrane protein that has a …

Apr 29, 2021 · Transforming growth factor β (TGFβ) signaling plays critical roles in reproductive development and function. TGFβ ligands signal through the TGFβ receptor type 2 …

Feb 9, 2025 · Integrative Network Analysis Combined with Quantitative Phosphoproteomics Reveals Transforming Growth Factor-beta Receptor type-2 (TGFBR2) as a Novel Regulator of …

HGNC Approved Gene Symbol: TGFBR2. Cytogenetic location: 3p24.1 Genomic coordinates (GRCh38) : 3:30,606,356-30,694,142 (from NCBI) By screening a human hepatoma cell cDNA …

TGF-β is a pluripotent cytokine that mediates its effects through a receptor composed of TGF-β receptor type II (TGFBR2) and type I (TGFBR1). The TGF-β receptor can regulate Smad and …