Human T follicular helper cells and their impact on IgE and IgG4 ...
Our current review provides the molecular characteristics of human Tfh cells, the differentiation pathways of Tfh subsets, mechanisms by which Tfh subsets induce IgE and IgG4 production, …
Frontiers | Pathogenic roles of follicular helper T cells in IgG4 ...
Jun 7, 2024 · Emerging evidence suggests that follicular helper T (Tfh) cells may play a critical role in the pathogenesis of IgG4-RD. Moreover, recent insights into the pathological roles …
Human T follicular helper cells and their impact on IgE and IgG4 ...
Jan 1, 2025 · Our current review provides the molecular characteristics of human Tfh cells, the differentiation pathways of Tfh subsets, mechanisms by which Tfh subsets induce IgE and …
Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in ...
Jun 1, 2020 · Follicular helper CD4 + T (Tfh) cells have a critical role in IgG4 production by B cells in IgG4-related disease (IgG4-RD). Recent studies including ours showed that SLAMF7 + CD4 …
Aberrant Expansion and Function of Follicular Helper T Cell
Furthermore, the ability of circulating Tfh (cTfh) cell subsets to induce B cell proliferation, apoptosis, and differentiation and to produce IgG4 was explored in cell cocultures in vitro. …
Enhanced IgG4 production by follicular helper 2 T cells and the ...
Jul 13, 2016 · The number of activated follicular helper T (Tfh) cell subsets, and total Tfh cell subsets, plasmablasts, and serum IgG4 level after glucocorticoid (GC) treatment in patients …
Distinct disease-specific Tfh cell populations in 2 different fibrotic ...
Our analysis revealed a novel subset of IL-10 + LAG3 + Tfh cells infiltrating the affected organs of IgG 4 -RD patients. In contrast, IL-13 + Tfh cells and type 2 immune cells infiltrated those of …
New insights into IgG4-related disease: emerging new CD4
Infiltration of activated T follicular helper (Tfh) cells is observed in affected tissues of IgG4-RD. Such Tfh cells have a greater capacity than tonsillar Tfh cells to help B cells produce IgG4. …
Pathogenic roles of follicular helper T cells in IgG4-related disease ...
Jun 7, 2024 · Emerging evidence suggests that follicular helper T (Tfh) cells may play a critical role in the pathogenesis of IgG4-RD. Moreover, recent insights into the pathological roles …
IgG4-related disease and other fibro-inflammatory conditions
6 days ago · IgG4-related disease (IgG4-RD) is a fibro-inflammatory disorder usually characterized by multi-organ involvement. ... Munemura, R. et al. Distinct disease-specific Tfh …
- Some results have been removed