
Response of the Urothelial Carcinoma Cell Lines to Cisplatin
Herein, we have examined CDDP response in a panel of the urothelial carcinoma cell (UCC) lines. We characterized these cell lines with regard to viability after CDDP treatment, as well …
EHHADH contributes to cisplatin resistance through regulation by …
In order to elucidate the mechanism of cisplatin resistance, we established cisplatin-resistant BC cell lines (CDDP-R-BOY and CDDP-R-T24). Then, small-RNA sequence analyses were …
Chemoimmunosensitization of the T24 human bladder cancer line …
We investigated whether CDDP, 5-FU and anti-Fas mAb synergize in cytotoxicity and apoptosis against the T24 bladder cancer line. Cytotoxicity was monitored by a one day microculture …
Incuba- tion of T24 or T24/CDDP cells with the c-myc antisense oligonucleotide increased the intracellular accumulation of CDDP, but not the accumulation of 5-FU. Conclusions.
Characterization and treatment of gemcitabine‐ and …
Apr 29, 2023 · GEM‐R‐BOY/T24 (A), CDDP‐R‐BOY/T24 (B), and parental BOY/T24 cells (C) were treated with control (DMSO) or Compound 3144 (5 μ m) for 48 h, and Spheroid …
A novel circular RNA (hsa_circRNA_102336), a plausible biomarker ...
Jun 1, 2020 · Overexpression of circ_102336 dramatically increased the cell proliferation viability of T24 and 5637 cells, while knockdown of circ_102336 exhibited opposite effects. Moreover, …
Enhancement of sensitivity of urinary bladder tumor cells to …
Nov 1, 1994 · However, combination treatment with the c-myc antisense oligonucleotide and CDDP resulted in a synergistic cytotoxic effect on T24 cells and two freshly derived UBT cells. …
MicroRNA-101-3p advances cisplatin sensitivity in bladder
Jun 2, 2019 · In T24/CDDP cells, the up-regulation of miR-101-3p decreased the half maximal inhibitory concentration (IC50) to CDDP, depressed the expression of MRP1 protein, promote …
人膀胱癌顺铂耐药细胞株T24/CDDP的建立和鉴定及耐药机制研究
建立人膀胱癌顺铂 (CDDP)耐药细胞株T24/CDDP,鉴定其生物学特性,并探讨其对CDDP耐药的机制。 采用CDDP浓度逐步递增联合大剂量CDDP冲击方法,在体外连续诱导、培养膀胱癌细胞 …
Circ_0058063 contributes to cisplatin-resistance of bladder cancer ...
Mar 23, 2022 · In our study, we verified that circ_0058063 expression levels were increased in CDDP-resistance BC tissues and cell lines and was associated with poor prognosis, and …