
Survivin - Wikipedia
Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. [5] Survivin is a member of the inhibitor of …
Survivin at a glance - PMC
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating …
Survivin: A molecular biomarker in cancer - PMC - PubMed …
Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases and blocks cell death, is highly expressed in most cancers and is associated with a poor clinical …
Survivin: a unique target for tumor therapy - Cancer Cell …
Jun 23, 2016 · Expression of Survivin in tumours correlates with not only inhibition of apoptosis and a decreased rate of cell death, but also resistance to chemotherapy and aggressiveness …
Validating survivin as a cancer therapeutic target - Nature
A survivin homologue in Xenopus laevis controls the enzymatic activity of Aurora kinase, a multifunctional regulator of mitosis.
Survivin as a biological biomarker for diagnosis and therapy
Jun 21, 2021 · Survivin (SVN) is both an attractive biological marker for diagnosis and a compelling target for therapy in both autoimmune diseases and cancer. This is particularly true …
Survivin: A molecular biomarker in cancer - PubMed
Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases and blocks cell death, is highly expressed in most cancers and is associated with a poor clinical …
Targeting survivin for cancer therapy: Strategies, small molecule ...
Dec 15, 2023 · Survivin, a bow-tie-shaped anti-apoptotic protein, is one of the key members of the Inhibitor-of-Apoptosis Protein (IAP) family. It is encoded by the BIRC5 (Baculoviral Inhibitor of …
Survivin: a unique target for tumor therapy - PMC - PubMed …
Survivin is the smallest member of the Inhibitor of apoptosis (IAP) family of proteins, involved in inhibition of apoptosis and regulation of cell cycle. These functional attributes make Survivin a …
Survivin – biology and potential as a therapeutic target in ... - PMC
Survivin is a member of the inhibitor-of-apoptosis proteins (IAPs) family; its overexpression has been widely demonstrated to occur in various types of cancer. Overexpression of survivin also …
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