SRY-box transcription factor 3, SOX3, is a transcription factor that is encoded by the SOX3 gene. This gene is responsible for ensuring proper embryonic development and determining the fate …

Mar 30, 2025 · SOX3 (SRY-Box Transcription Factor 3) is a Protein Coding gene. Diseases associated with SOX3 include Intellectual Developmental Disorder, X-Linked, With …

Transcription factor SOX3 upregulated pro-apoptotic genes expression in human breast cancer. A SOX3 duplication and lumbosacral spina bifida in three generations. LINC00662 Promotes …

Some SOX TFs suspend neural progenitors in proliferative, stem-like state and prevent their differentiation. SOX proteins function as pioneer factors that occupy silenced target genes and …

SOX3 is a protein that belongs to the B group of the large Sox proteins. It is involved in neural ectoderm specification and acts as a mesodermal suppressor in the ectoderm by negatively …

Upon differentiation into NPCs, Sox2 collaborates with Sox3 to relocate from pluripotent to neural specific gene enhancers. These enhancers are either active in NPCs and hence carry the …

Apr 21, 2020 · Using a panel of spermatogonial cell marker genes, we demonstrate that Sox3 is expressed within the committed progenitor fraction of the undifferentiated spermatogonial pool. …

May 29, 2024 · By focusing on the role of Sox2 and Sox3 in the early phases of differentiation, we furthermore show that Bcas1, Enpp6, Zfp488 and Nkx2.2 are direct targets of Sox2 and Sox3 …

Stevanovic et al. (1993) cloned and characterized SOX3. A reverse transcription coupled with PCR (RT-PCR) was used to amplify SRY-related transcripts expressed during embryogenesis …

The ability of SOX3 to counteract astrocyte gene expression and maturation in vitro raises the possibility that SOX3 hinders progenitor cells in the developing CNS from committing to …