Sep 15, 2017 · View credits, reviews, tracks and shop for the 2017 CD release of "Apollo / Rive Gauche" on Discogs.

Here, we summarize the molecular properties of the CD1 isoforms, their lipid antigens, and CD1-restricted T cells, with particular focus on CD1a. We then discuss the roles that CD1a-reactive T cells play in several diseases.

Moving from molecules to diseases, new research approaches emphasize human CD1-transgenic mouse models and the study of human polyclonal T cells in vivo or ex vivo in disease states.

Cd1-restricted T cells are part of the unconventional T cell family, they are stimulated by exposure to CD1 + antigen presenting cells (APCs). Many CD1-restricted T cells are rapidly stimulated to carry out helper and effector functions upon interaction with …

Mar 20, 2024 · These CD1–lipid complexes are recognized by T cell receptors (TCRs) expressed on T cells, either through dual recognition of CD1 and lipid or in a new model whereby the TCR directly contacts CD1, thereby triggering an immune response.

Dec 13, 2022 · In this report, we draw from this recent inspiration to outline some key insights and emerging directions for the field. We discuss new themes regarding antigen presentation by CD1 and MR1 and modes of antigen recognition by CD1- and MR1-restricted T cell receptors (TCRs).

CD1 molecules present foreign and self lipids to diverse T cells and natural killer T (NKT) cells. Whereas the clonally restricted diverse T cells mediate adaptive immunity to microbial lipid...

Sep 21, 2015 · New evidence shows that T cells recognizing CD1 or MR1 proteins are abundant in humans, supporting the use of lipid and small-molecule antigens as a new approach to therapy. In early work,...

CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells.