SOD enzymes catalyze the dismutation of superoxide (O 2 •-), generating hydrogen peroxide (H 2 O 2). The catalase (CAT), glutathione peroxidases (GPXs), and PRXs convert H 2 O 2 into …

Superoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O − 2) anion radical into normal molecular oxygen (O 2) …

We propose that mitochondrial superoxide dismutase (SOD2) is a major system converting diffusion-restricted superoxide radicals derived from the electron transport chain into highly …

Superoxide dismutase 1 (SOD1) is an abundant copper/zinc enzyme found in the cytoplasm that converts superoxide into hydrogen peroxide and molecular oxygen. Tetrathiomolybdate (ATN …

Jun 4, 2018 · In this review, we discuss studies in model organisms and humans, which reveal the dual roles of SOD enzymes in controlling damage and regulating signaling. Superoxide …

Oct 14, 2021 · SOD removes excess superoxide radicals (O2−) by converting them to hydrogen peroxide (H2O2) and molecular oxygen (O2). Several superoxide dismutase enzymes have …

Superoxide dismutase (SOD) is an important neuroprotective enzyme that converts harmful superoxide radicals (O 2 −) to the less toxic, hydrogen peroxide (H 2 O 2). Three major SOD …

Sep 8, 2017 · Superoxide dismutase (SOD) is a ubiquitous antioxidant enzyme that catalytically converts the superoxide radical to hydrogen peroxide (H 2 O 2 ). In mammals, high SOD …

May 15, 2007 · Numerous reports of the effects of overproduction of SODs have been explained on the basis of increased H2O2 production by the catalyzed dismutation of O2-. In this review …

Recent evidence suggests that in each subcellular location, SODs catalyze the conversion of O 2•− H 2 O 2, which may participate in cell signaling. In addition, SODs play a critical role in …