Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).

Feb 5, 2025 · Sirolimus weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection happens when the immune system treats the new organ as an invader and attacks it. Sirolimus is used with other medicines to prevent organ rejection after a kidney transplant.

Apr 1, 2025 · Sirolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also reduce the body's ability to fight infections. You and your doctor should talk about the benefits of this medicine as well as the risks.

Sirolimus is a medication that decreases your immune system’s response to a transplanted organ to prevent rejection. It can also treat lymphangioleiomyomatosis. This condition causes damage to your lung tissue that results in an inability of fully oxygenate blood, fluid in …

Jan 14, 2025 · Overview: Sirolimus is used to prevent kidney transplant rejection and to treat lymphangioleiomyomatosis (LAM), a rare lung disease. It prevents organ rejection by suppressing the...

Mar 17, 2025 · Rapamune (sirolimus) is used to prevent rejection in people who have received a kidney transplant. Learn about side effects, interactions and indications.

May 10, 2024 · It is used after a kidney transplant to keep the body from rejecting the kidney. It is used to treat a lung disease called lymphangioleiomyomatosis (LAM). It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I …

Sirolimus is used in combination with other medications to prevent rejection of kidney transplants. Sirolimus is in a class of medications called immunosuppressants. It works by suppressing the body's immune system. How should this medicine be used? Sirolimus comes as a tablet and a solution (liquid) to take by mouth.

Jun 1, 2023 · Learn about sirolimus (Rapamune) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives.

Sirolimus is an mTOR inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in patients aged ≥13 years receiving renal transplants: Patients at low-to moderate-immunologic risk: Use initially with cyclosporine (CsA) and corticosteroids. CsA withdrawal is recommended 2 to 4 months after transplantation .