Serglycin, also known as hematopoietic proteoglycan core protein or secretory granule proteoglycan core protein, is a protein that in humans is encoded by the SRGN gene. [5] It is …

Serglycin is a proteoglycan found in hematopoietic cells and endothelial cells. It has important functions related to formation of several types of storage granules.

Oct 2, 2007 · Serglycin is a proteoglycan found in hematopoietic cells and endothelial cells. It has important functions related to formation of several types of storage granules.

It has been shown that serglycin is highly expressed by tumor cells and promotes their aggressive phenotype and confers resistance against drugs and complement system attack. Apart from its …

Mar 30, 2025 · SRGN (Serglycin) is a Protein Coding gene. Diseases associated with SRGN include Mucinoses and Central Corneal Ulcer . Among its related pathways are Response to …

Serglycin is a proteoglycan that has its core peptide coded by the gene SRGN in humans. It belongs to a family of small proteoglycans with serine-glycine dipeptide repeats and is …

Sep 23, 2021 · Here we show that the proteoglycan Serglycin (SRGN) secreted by neoplastic stromal cells plays a crucial role in the formation of MGCs and tumorigenesis in GCTB.

Nov 15, 2011 · Based on these findings, serglycin is emerging as a structural and functional chameleon, with radically different properties depending on its exact cellular and …

Serglycin is a proteoglycan composed of a relatively small (~17 kDa) core protein to which sulfated glycosaminoglycans of either heparin, heparan sulfate or chondroitin sulfate types are …

Serglycin is a major proteoglycan in polarized human endothelial cells and is implicated in the secretion of the chemokine GROalpha/CXCL1. Serglycin is of importance for secretory …