The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase ...
May 18, 2017 · Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. We demonstrate that the N 6 -adenosine …
mTORC1 stimulates cell growth through SAM synthesis and m6A …
Through the control of MAT2A and WTAP levels, mTORC1 signaling stimulates m 6 A RNA modification to promote protein synthesis and cell growth. A decline in intracellular SAM levels …
mTORC1 stimulates cell growth through SAM synthesis and m6A …
May 20, 2021 · Through the control of MAT2A and WTAP levels, mTORC1 signaling stimulates m 6 A RNA modification to promote protein synthesis and cell growth. A decline in intracellular …
The Role of the m6A RNA Methyltransferase METTL16 in Gene
Dec 8, 2022 · The characterization of the less familiar family member METTL16 has uncovered a new function of the m6A methylation apparatus, namely the fine-tuning of the cellular levels of …
Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. We demonstrate that the N6-adenosine …
A metabolic labeling method detects m6A transcriptome-wide …
Apr 27, 2020 · The authors developed a metabolic labeling method via incorporation of allyl-SAM analogs to profile transcriptome-wide m6A at base resolution, which enables identification of …
The Role of the m6A RNA Methyltransferase METTL16 in Gene …
Dec 8, 2022 · Methionine adenosyltransferase (MAT or SAM synthetase) catalyzes the formation of SAM from methionine and ATP. Methyltransferases transfer the methyl group from SAM to …
The U6 snRNA m6A methyltransferase METTL16 regulates SAM …
Maintenance of proper levels of the methyl donor S-adenosylmethionine (SAM) is critical for a wide variety of biological processes. We demonstrate that the N 6 -adenosine …
m6A‐mediated alternative splicing coupled with nonsense…
Jun 21, 2021 · Autoregulation of SAM synthetase gene expression by alternative pre‐mRNA splicing in C. elegans demonstrated in this study emphasizes the importance of maintaining …
mTORC1 stimulates cell growth through SAM synthesis and m6A …
Through the control of MAT2A and WTAP levels, mTORC1 signaling stimulates m 6 A RNA modification to promote protein synthesis and cell growth. A decline in intracellular SAM levels …