Saba Ghassemi, PhD Research Assistant Professor of Pathology and Laboratory Medicine. Dr. Saba Ghassemi graduated with a Master’s degree in Mechanical Engineering from Villanova University. She then completed her PhD at Columbia University, training under Drs. Michael Sheetz and James Hone.

Engineering quiescent Chimeric Antigen Receptor (CAR) T cells for adoptive immunotherapy; Developing genetic approaches to enhance CAR T cell function in solid tumors; Designing novel culture platforms to improve CAR T cell function and differentiation.

Shortened T cell culture with IL-7 and IL-15 provides the most potent chimeric antigen receptor (CAR)-modified T cells for adoptive immunotherapy.

Saba Ghassemi, PhD Research Assistant Professor of Pathology and Laboratory Medicine Perelman School of Medicine at the University of Pennsylvania Contact InformationCenter for Cellular Immunotherapies 3400 Civic Center Blvd 9-101 SPE Philadelphia, PA 19104 Tel: 215-898-5040 Email: [email protected]

Saba Ghassemi, Michael C Milone: Manufacturing Chimeric Antigen Receptor (CAR) T Cells for Adoptive Immunotherapy. Journal of Visualized Experiments 154 (no issue number): no page number, Dec 2019.

Ghassemi S, Martinez-Becerra FJ, Master AM, Richman SA, Heo D, Leferovich J, Tu Y, García-Cañaveras JC, Ayari A, Lu Y, Wang A, Rabinowitz JD, Milone MC, June CH, O'Connor RS. Enhancing Chimeric Antigen Receptor T Cell Anti-tumor …

Dr. Saba Ghassemi, an assistant professor of pathology and laboratory medicine at the University of Pennsylvania’s Perelman School of Medicine, understands that sometimes the best way to …

Dr. Saba Ghassemi is an Assistant Professor in the Department of Pathology and Laboratory Medicine and serves as a Principal Investigator at the Center for Cellular Immunotherapies at the University of Pennsylvania.

García-Cañaveras J, Heo D, Trefely S, Leferovich J, Xu C, Philipson B, Ghassemi S, Milone M, Moon E, Snyder N, June C, Rabinowitz J, O’Connor R. CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production. Cells. 2021;10 (9). …