Jul 30, 2020 · Regulation of ketone body utilizing genes, protein, and activity by streptozotocin (STZ)‐induced hyperglycemia. Gene expression from qPCR analysis showing expression of …

Dec 7, 2021 · Three ketone bodies exist: acetone, acetoacetate, and beta-hydroxybutyrate (β-OHB). β-OHB is the ketone body which is in highest concentration in the blood and is typically …

Mar 30, 2023 · Ketone bodies are a critical cardiac fuel and have diverse roles in the regulation of cellular processes such as metabolism, inflammation, and cellular crosstalk in multiple organs …

Nov 30, 2020 · These findings suggest that ketone body utilization seems to be facilitated in DKO hearts to compensate for reduced FA supply irrespective of STZ treatment.

May 26, 2023 · 3-Hydroxybutyrate (3HB) is a small ketone body molecule produced endogenously by the body in the liver. Previous studies have shown that 3HB can reduce blood glucose level …

Apr 2, 2025 · Ketone bodies can be used as an alternative energy and a metabolic signal molecule to affect the occurrence and development of many diseases, while the study on the …

In this review, we discuss, in the pathological context of cardiovascular risks, the current understanding of how ketone bodies, or a ketogenic diet, are able to modulate, trigger, or …

Jul 4, 2017 · STZ-induced diabetic mice showed severe hyperglycemia that correlated with a decrease in body weight and heart weight, resulting in a slight increase of heart to body weight …

By using an in situ rat hindquarter perfusion, we evaluated ketone body utilization and its metabolic effects in the resting muscle of 24 h fasted normal and streptozotocin (STZ)-diabetic …

Jun 1, 2008 · Acetoacetyl-CoA synthetase (AACS), an essential enzyme for the synthesis of fatty acid and cholesterol from ketone bodies, was found to be highly expressed in mouse adipose …