Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family.

Mar 16, 2025 · Gene target information for STAT1 - signal transducer and activator of transcription 1 (human). Find diseases associated with this biological target and compounds …

The signal transducer and activator of transcription (STAT) 1 protein plays a key role in the immune response against viruses and other pathogens by transducing, in the nucleus, the …

Nov 26, 2021 · The signal transduction and activator of transcription (STAT) family have six members: STAT1 (STAT1 has two splicing isoforms, STAT1α and STAT1β), STAT2, STAT3 …

Mar 30, 2025 · STAT1 (Signal Transducer And Activator Of Transcription 1) is a Protein Coding gene. Diseases associated with STAT1 include Immunodeficiency 31C and Immunodeficiency …

Title: STAT1 as a downstream mediator of ERK signaling contributes to bone cancer pain by regulating MHC II expression in spinal microglia.

Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors (PubMed:12764129, …

Complete activation of signal transducer and activator of transcription 1 (STAT1) requires phosphorylation at both Y701 and a conserved PMS 727 P sequence.

Mar 8, 2025 · STAT1 Employs Myeloid Cell-Extrinsic Mechanisms to Regulate the Neutrophil Response and Provide Protection against Invasive Klebsiella pneumoniae Lung Infection.

STAT1 is critical in signal transduction from both the type I interferons IFNA (see 147660) and IFNB (see 147640) and the type II interferon IFNG (147570). After IFNG stimulation, STAT1 is …