These mice may be useful in studying dendritic inhibitory interneurons such as Martinotti cells and Oriens-Lacunosum-Moleculare cells. While Sst-IRES-Cre was designed as a 3' knock-in …

Jun 24, 2021 · Here, we identify a population of somatostatin (TN SST) neurons in the mouse hypothalamic tuberal nucleus that are preferentially activated by palatable food. Activation of …

Nov 1, 2022 · We utilized the novel Easi- CRISPR system to generate two knock-in mouse strains with Cre recombinase in SST- and CCK-expressing cells and validated their utility in the …

In SOM-IRES-Cre mouse line [Sst tm2.1(cre)Zjh /J mice ], the Cre construct was targeted to the 3′UTR region of the sst gene. In this study, we characterized the molecular and physiological …

Genetic methods to target, record and control the activity of SST neurons in mice have revealed intriguing evidence for their role in decision making, synaptic plasticity and learning.

3 days ago · SST-Ai14 and PV-Ai14 mice were generated by crossing either homozygous SST-Cre mice (Sst tm2.1(cre)Zjh /J, Jackson Laboratory, #018973) or PV-Cre mice (B6.129P2 …

Jul 18, 2024 · To overcome this limitation, we backcrossed Sst-Cre and Vip-Cre mice to CBA mice to create normal-hearing offspring with the desired Cre transgenes. We confirmed that in …

Jun 19, 2017 · The neuropeptide somatostatin (SOM) is widely expressed in rodent brain and somatostatin-IRES-Cre (SOM-cre) mouse strains are increasingly used to unravel the …

Jun 19, 2017 · We show that Cre transgene insertion into the 3′UTR of the somatostatin gene leads to the selective and massive depletion of endogenous SOM in all tested brain regions.

These mice may be useful in studying dendritic inhibitory interneurons such as Martinotti cells and Oriens-Lacunosum-Moleculare cells. While Sst-IRES-Cre was designed as a 3' knock-in …