Sterol regulatory element-binding transcription factor 1 (SREBF1) also known as sterol regulatory element-binding protein 1 (SREBP-1) is a protein that in humans is encoded by the SREBF1 …

SREBPs are a family of membrane-bound transcription factors that activate genes encoding enzymes required for synthesis of cholesterol and unsaturated fatty acids. SREBPs are …

Mar 30, 2025 · SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1) is a Protein Coding gene. Diseases associated with SREBF1 include Ifap Syndrome 2 and Mucoepithelial …

Sterol regulatory element-binding proteins (SREBPs) are transcription factors that bind to the sterol regulatory element DNA sequence TCACNCCAC. [2] . Mammalian SREBPs are …

Sterol regulator element binding proteins (SREBPs) are a family of transcription factors involved in the biogenesis of cholesterol, fatty acids and triglycerides. They also regulate physiological …

Mar 22, 2019 · Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid biosynthesis and adipogenesis by controlling the expression of …

In this review, we first introduced the structure, activation, and key upstream signaling pathway of SREBP-1. Then, the potential targets and molecular mechanisms of SREBP-1-regulated …

Oct 8, 1993 · Sterol regulatory element 1 (SRE-1), a decamer (5′-ATC-ACCCCAC-3′) flanking the low density lipoprotein (LDL) receptor gene, activates transcription in sterol-depleted cells and …

Jul 25, 2023 · Our study unravels an SREBP-1-autophagy-LD-CE hydrolysis pathway that plays an important role in maintaining membrane cholesterol homeostasis while providing a potential …

Aug 29, 2017 · Two isoforms of SREBP1 are formed from the transcription of the SREBP1 gene (SREBF1) from different promoters. SREBP1c is the predominant isoform expressed in most …