Mar 6, 2019 · Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are now believed to be variants of the same condition, distinct from erythema multiforme. SJS/TEN is a rare, acute , serious, and potentially fatal skin reaction in …

SJS images, TEN images, Stevens Johnson syndrome images, Toxic epidermal necrolysis images ...

Feb 19, 2017 · Stevens Johnson syndrome /toxic epidermal necrolysis (SJS/TEN) is a very severe and acute skin disease, almost always caused by a drug. SJS/TEN is characterised by an extensive necrosis and detachment of the epidermis, which involves skin and mucosal surfaces (genitals, eyes, and mouth).

Stevens Johnson syndrome – toxic epidermal necrolysis (SJS/TEN) Acute generalised exanthematous pustulosis (AGEP) Patients with the following symptoms/signs should be hospitalised for specialist assessment and supportive care. Erythroderma (whole-body involvement) High fever or significant malaise; Any mucosal involvement; Skin tenderness ...

Systemic symptoms such as fever and malaise, are absent or mild in EM but are prominent in SJS/TEN, especially in the prodromal period. Fever, when present in EM, is mild ( 38.5 C) compared to high fevers with SJS/TEN. Patients with SJS/TEN are systemically ill. Outcome and prognosis – virtually all patients with EM recover with no sequelae.

It may have overlapping features with Stevens–Johnson syndrome / toxic epidermal necrolysis (SJS/TEN) and acute generalised exanthematous pustulosis (AGEP). Who gets drug hypersensitivity syndrome? Drug hypersensitivity syndrome is relatively rare. It mainly affects adults and is equal in incidence in males and females.

Erythema multiforme (EM) is conventionally separated into EM minor and EM major. It is now separated from Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (T.E.N.). Clinical features EM minor. EM is more common in men than women and 50% are under 20 years of age.

Oct 3, 2016 · SJS/TEN often presents with a few days of prodromal illness with fever (> 39 C), malaise, cough, a blocked or runny nose, sore throat and sore eyes. The rash then appears and extends over 5–7 days. It usually starts on the face, chest, and the proximal limbs, and then spreads widely.

Triggers for Stevens Johnson syndrome / toxic epidermal necrolysis. Authoritative facts about the skin from DermNet New Zealand.

SJS/TEN can cause permanent scarring leading to blindness and deformity. How are drug eruptions diagnosed? A careful history, skin and general physical examination are necessary to diagnose a drug eruption and to assess its severity. Determine any previous exposure to the medication(s) under suspicion.