The SH-SY5Y cell line is a thrice cloned subline of the neuroblastoma cell line SK-N-SH (ATCC HTB-11), which was established in 1970 from a metastatic bone tumor from a 4-year-old …

SH-SY5Y is a human derived cell line used in scientific research. The original cell line, called SK-N-SH, from which it was subcloned was isolated from a bone marrow biopsy taken from a four …

SH-SY5Y is a thrice-subcloned cell line derived from the SK-N-SH neuroblastoma cell line. It serves as a model for neurodegenerative disorders since the cells can be converted to various …

In this study, we present an optimized neuronal differentiation protocol for SH-SY5Y that requires only two work steps and 6 days. After differentiation, the cells present increased levels of ATP …

Transformed neuronal-like cell lines can be used in vitro to overcome this limitation. However, several caveats exist when utilizing cells derived from malignant tumors. In this context, the …

Sep 8, 2021 · The SH-SY5Y cell line is a comparatively homogeneous neuroblast-like cell line, which exhibits neuronal marker enzyme activity (tyrosine and dopamine-β-hydroxylases), …

SH-SY5Y is a human-derived cell line that originated from subcloning of the SK-N-SH neuroblastoma cell line in 1970. The parent cell line, SK-N-SH, was developed from the bone …

Sep 1, 2022 · The SH-SY5Y human neuroblastoma cell line (ATCC® CRL-2266™) is one of the most used cell lines in neurosciences, either undifferentiated or differentiated into neuron-like …

Feb 11, 2025 · Explore the unique features and growth phases of SH-SY5Y cells, focusing on their receptor expression and signal transduction pathways. SH-SY5Y cells, a human-derived …

SH-SY5Y cells have been used to study the molecular and cellular mechanisms underlying the effects of some of the PD-related toxins, to perform functional studies on familial PD genes, …