S100A4, a member of the S100 calcium-binding protein family secreted by tumor and stromal cells, supports tumorigenesis by stimulating angiogenesis.

S100A4, also called fibroblast-specific protein 1 (Fsp1) or metastasin 1 (MTS1), is a member of the large family of S100 proteins, containing two EF-hand Ca 2+-binding motifs, and with a …

Mar 30, 2025 · S100A4 (S100 Calcium Binding Protein A4) is a Protein Coding gene. Diseases associated with S100A4 include Follicular Adenoma and Anaplastic Thyroid Carcinoma. …

Feb 9, 2022 · Furthermore, we identify S100A4 as a regulator of immune suppressive T and myeloid cells in GBM and demonstrate that deleting S100a4 in non-cancer cells is sufficient to …

S100A4 is a Ca 2+ -binding protein that performs an important role in metastasis. It is also known for its antitumor functions. S100A4 is expressed by a specialized subset of CD 4+ CD 25+ …

We provide evidence that S100A4 regulation of immune cell function has a profound role in promoting the pathogenesis of cancer and pro-inflammatory conditions. Finally, we discuss …

S100A4 may be a promising marker indicative of the aggressive behavior and prognosis of gastric carcinomas. S100A4 as a likely tumour marker for hepatocellular carcinoma that correlates …

Mar 6, 2008 · S100A4 belongs to the S100 family of proteins that contain two Ca 2+-binding sites including a canonical EF-hand motif. S100A4 is involved in the regulation of a wide range of …

The metastasis-promoting S100A4 protein, a member of the S100 family, has recently been discovered as a potent factor implicated in various inflammation-associated diseases. S100A4 …

Mar 16, 2021 · While S100A4 has long been implicated mainly in tumorigenesis and metastatization, mounting evidence shows that S100A4 is a key player in promoting pro …