The renal outer medullary potassium channel (ROMK) is an ATP-dependent potassium channel (K ir 1.1) that transports potassium out of cells. It plays an important role in potassium …

Aug 13, 2019 · Magnesium helps limit potassium excretion into the urine by controlling the ROMK pump. I hope this helps you understand why you need to correct the magnesium when a …

The apically located renal outer medullary K + (ROMK) channel provides a pathway for K + to recycle from cell to lumen, and ensures an adequate supply of K + to sustain Na +-K +-2Cl − …

The ability of intracellular and extracellular Mg2+ to block secretory K+ currents through ROMK channels under physiologic conditions is incompletely understood. We expressed ROMK2 …

Oct 1, 2009 · ROMK encodes a major potassium secretory channel in the kidney. In distal nephron principal cells, ROMK1 and ROMK3 form the predominant 30-pS potassium channel. …

Apr 23, 2021 · For one, the ROMK channel also works in reverse, and would permit potassium back into the cell if the conditions were favourable. Additionally, there is an apical H + /K + …

Here we provide a comprehensive guide to ROMK, spanning from the physiology in the kidney to the organization and regulation by intracellular factors to the structural basis of its function at …

We measured the activities of epithelial Na channels (ENaC) and ROMK channels in the distal nephron of the mouse kidney and assessed their role in the process of K + secretion under …

Mar 30, 2009 · Here we provide a compre-hensive guide to ROMK, spanning from the physiology in the kidney to the organization and regulation by intracellular factors to the structural basis of …

In recent years, understanding of the physiological role of the renal outer medullary potassium (ROMK) channels, has shown an intriguing pharmacological target for developing an …