Aug 22, 2019 · A revised tool to assess risk of bias in randomized trials (RoB 2) Welcome to the website for the RoB 2 tool. The current version (22 August 2019), suitable for individually-randomized, parallel-group trials.

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Welcome to our pages for risk of bias tools for use in systematic reviews. RoB 2 tool (revised tool for Risk of Bias in randomized trials) ROBINS-E tool (Risk Of Bias in non-randomized Studies - of Exposures)

The Risk of Bias 2 (RoB 2) tool is an update to the original risk of bias tool that launched in 2008. The relevant chapter in the Cochrane Handbook for Systematic Reviews of Interventions Chapter 8, titled ‘Assessing risk of bias in a randomized trial’.

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The RoB 2 tool provides a framework for assessing the risk of bias in a single result (an estimate of the effect of an experimental intervention compared with a comparator intervention on a particular outcome) from any type of randomized trial.

The choice of risk of bias tools (RoB tools) is not straightforward for reviews of NRS, although methodological tools for assessing the risk of bias in randomized controlled trials (RCT) are more well-established, with the Cochrane Collaboration’s RoB Tool now considered the standard .

Risk of bias (RoB) The resources in this collection mostly cover the Cochrane risk-of-bias tool for randomized trials ( RoB 2 ). Under 'Risk of bias tools' there is also guidance on ROBINS-I tool for assessing risk of bias in non-randomized studies.

An Excel tool to implement RoB 2 (contains macros; download to your computer before using; some text is slightly out of date). We have also made available a version of RoB 2 for cluster-randomized trials. and a version of RoB 2 for crossover trials .