Jul 1, 2016 · The present study aimed to test whether light responsive neurons in the rat SCN display an electrophysiological phenotype that distinguishes them from non‐responsive cells, …

Jan 29, 1999 · Cell lines derived from the rat suprachiasmatic nucleus (SCN) were screened for circadian clock properties distinctive of the SCN in situ. Immortalized SCN cells generated …

Intracerebroventricular administration of neuromedin S in rats activates SCN neurons and has the capability to induce non-photic type of phase shifts in the circadian rhythm of locomotor activity.

May 4, 2004 · In the rat SCN, ventrolateral (including VIP) neurons receive direct retinal input, and they in turn project to ipsilateral, dorsomedial neurons [10]. Somehow the 22 hr LD cycle has …

Mar 26, 2004 · Immortalized SCN2.2 cells retain most biochemical and biophysical characteristics of the native rat SCN including the expression of clock genes and circadian regulatory …

Using a luciferin-luciferase chemiluminescent assay, we have demonstrated that ATP levels fluctuate rhythmically within both SCN2.2 cell cultures and the rat SCN in vivo. SCN2.2 cells …

May 11, 2005 · To determine whether immortalized cells derived from the rat SCN (SCN2.2) retain these intrinsic rhythm-generating properties, oscillatory behavior of the SCN2.2 …

Valuable tool for studies relating to the regulation of the central mammalian pacemaker function and the development of the suprachiasmatic nucleus (SCN) cell types (Kerafast=EUT500). …

Feb 17, 2014 · Here, we generated a subclone of an SCN progenitor cell line expressing Ca2+ sensors (SCN2.2YC) and compared its 5-HT receptor signalling with that of rat SCN neurons …

Jun 12, 1998 · Discovered approximately 25 years ago, the SCN contains the master oscillator that drives locomotor activity rhythms in mammals.