An optimized acetylcholine sensor for monitoring in vivo …
Sep 28, 2020 · Here we optimized the GRAB ACh (GPCR-activation-based ACh) sensor to achieve substantially improved sensitivity in ACh detection, as well as reduced downstream …
Potentiation of Acetylcholine-Induced Relaxation of Aorta in Male …
Concentration-response curves to acetylcholine (ACh) in control and UCD-T2DM rat aorta. Relaxation responses to cumulative concentrations of ACh (10 –8 to 10 –5 M) in intact aortic …
Muscarinic M(3) facilitation of acetylcholine release from rat ...
Adenosine released from stimulated myenteric neurons modulates ACh release preferentially via facilitatory A(2A) receptors. In this study, we investigated how muscarinic and adenosine …
Novel regulatory systems for acetylcholine release in rat ... - PubMed
Here, we investigated regulatory mechanisms for acetylcholine (ACh) release from cholinergic neurons by performing superfusion experiments with rat striatal segments after labelling the …
Analysis of L-NAME-dependent and -resistant responses to
The present data suggest that the hindlimb vasodilator response to ACh in the rat is mediated by two mechanisms with an initial ChTX- and apamin-sensitive, L-NAME-resistant phase not …
Analysis of - American Physiological Society Journal
Feb 1, 2008 · The present data suggest that the hindlimb vasodilator response to ACh in the rat is mediated by two mechanisms with an initial ChTX- and apamin-sensitive, l -NAME-resistant …
The Inhibitory Mechanism on Acetylcholine-Induced Contraction …
Nov 12, 2018 · Rats in the DM group received an intraperitoneal injection of 65 mg/kg streptozotocin and measured blood glucose level after 14 days to confirm DM. Bladder smooth …
Impaired relaxation of cerebral arteries in the absence of elevated ...
Sep 17, 2010 · This study evaluated endothelium-dependent vascular relaxation in response to acetylcholine (ACh) in isolated middle cerebral arteries (MCA) from Dahl salt-sensitive (Dahl …
Acetylcholine muscarinic M2 receptor maintains human Schwann …
2 days ago · We previously investigated the presence and role of ACh muscarinic receptors, and in particular of M2 muscarinic subtype, before in rat and human SCs [22,23,24] and then in rat …
Antihypertensive Mechanism of Orally Administered Acetylcholine …
Our latest study revealed a selective BP-lowering effect of orally administered ACh in hypertensive rats, but not in normotensive rats, and indicated the involvement of the …
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