RAB7 is a small GTPase that has the potential of causing malignancy from over 35 tumor types. It is found that RAB7 is an early induced melanoma driver whose levels can define metastatic …

Mar 30, 2025 · RAB7A (RAB7A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB7A include Charcot-Marie-Tooth Disease, Axonal, Type 2B and …

Feb 9, 2025 · This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also …

RAB7 is a small guanosine triphosphatase (GTPase) extensively studied as regulator of vesicular trafficking. Indeed, its role is fundamental in several steps of the late endocytic pathway, …

Rab7 is a protective factor for intervertebral discs and could delays intervertebral disc degeneration through the inhibition of the p38MAPK pathway. Rab7 has a novel function in …

Rab7 (or Ypt7 in yeast) is one of the well-characterized members of the Rab family small GTPases, which serve as master regulators of membrane trafficking in eukaryotes. It localizes …

Rab7 is a late endosome-/lysosome-associated small GTPase, perhaps the only lysosomal Rab protein identified to date. Rab7 plays critical roles in the endocytic processes.

Apr 7, 2024 · This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also …

Jul 14, 2014 · Alonso-Curbelo et al. identify a unique dependency in melanoma on the small GTPase RAB7 due to regulation by both oncogenic and lineage-specific factors. RAB7 …

Feb 27, 2023 · RAB7 specifically controls the transition of early endosomes into the late-endosomal/lysosomal system and subsequent degradation of cargos associated with target …