Mar 30, 2025 · RAB14 (RAB14, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB14 include Cystic Fibrosis and Warburg Micro Syndrome 1 . Among its related pathways are Innate Immune System and Vesicle-mediated transport .

Ras-related protein Rab-14 is a protein that in humans is encoded by the RAB14 gene. [5] [6] [7]

RAB14 acts as molecular switches that shift between a GDP-bound inactive state and a GTP-bound active state and regulates circulation of vesicles between the Golgi and endosomal compartments. In present study, we investigated the roles of …

Rab GTPases are localized to various intracellular compartments and are known to play important regulatory roles in membrane trafficking. Here, we report the subcellular distribution and function of Rab14.

Rab GTPases define the vesicle trafficking pathways underpinning cell polarization and migration. Here, we find that Rab4, Rab11, and Rab14 and the candidate Rab GDP-GTP exchange factors (GEFs) FAM116A and AVL9 are required for cell migration.

Feb 9, 2025 · RAB14 as a novel physiological inhibitor of human erythropoiesis. the miR-451/RAB14 interaction plays an important role in the enhancement of radiosensitivity in NPC cells. Data indicate that myosin Va interacted with multiple new …

Aug 9, 2023 · Based on the hypothesis that autophagy-related gene RAB14 abnormal expression may mediate a crosstalk of the autophagy and EMT during bladder cancer metastasis, we focused on investigating...

Rab14 Facilitates Growth and Invasion of Lung Cancer Cells. Rab14 protein levels in BEAS-2B and lung cancer cell lines including H460, H358, LK2, A549, H1299 and H292 were detected using Western blot . The cancer cell lines had relatively high protein expression.

Rab GTPases are localized to various intracellular compartments and are known to play important regulatory roles in membrane trafficking. Here, we report the subcellular distribution and function of Rab14.

Sep 18, 2020 · Functionally, Rab14 overexpression increased growth rate, colony formation, invasion/migration ability and cell cycle progression, while Rab14 siRNA decreased the cell proliferation rate, colony numbers and inhibited invasion/migration ability and cell …