Runx1 Deficiency Protects Against Adverse Cardiac Remodeling …
Jan 2, 2018 · Experiments performed with a newly generated cardiomyocyte-specific Runx1-deficient mouse reveal that reducing Runx1 function preserves myocardial contractility and …
Runx1 contributes to articular cartilage maintenance by
May 21, 2019 · To investigate chondrocyte regulation by Runx1, we analysed interactions with co-factors and downstream molecules. Runx1 enhanced cartilage matrix production in …
The transcription factors T-bet and Runx are required for the …
Because Runx1 is required for the survival of CD4 + T cells, in part by regulating IL-7Rα expression, and Runx1-deficient mice have a substantial reduction in peripheral CD4 + T cells …
RUNX1 Gene - GeneCards | RUNX1 Protein | RUNX1 Antibody
Mar 30, 2025 · RUNX1 (RUNX Family Transcription Factor 1) is a Protein Coding gene. Diseases associated with RUNX1 include Platelet Disorder, Familial, With Associated Myeloid …
Runx1 contributes to articular cartilage maintenance by …
May 21, 2019 · To investigate chondrocyte regulation by Runx1, we analysed interactions with co-factors and downstream molecules. Runx1 enhanced cartilage matrix production in …
Runx1 Regulates Myeloid Precursor Differentiation Into …
Runt-related transcription factor 1 (Runx1), a master regulator of hematopoiesis, is expressed in preosteoclasts. Previously we evaluated the bone phenotype of CD11b-Cre Runx1fl/fl mice …
Targeting Runx1 prevents mitochondrial damage in the border …
Dec 31, 2022 · Overall, our results confirm the translational potential of Runx1 as a novel therapeutic target post-MI and identifies a new mechanism linking Runx1 to mitochondrial …
Targeting RUNX1 as a novel treatment modality for pulmonary …
Jan 9, 2022 · In the current study, we aimed to determine whether RUNX1 inhibition was sufficient to reverse Sugen/hypoxia (SuHx)-induced pulmonary hypertension (PH) in rats. We also …
Runx1 contributes to articular cartilage maintenance by …
May 21, 2019 · We obtained primary articular chondrocytes from Runx1fl/fl mice, and transduced adenoviral GFP, Runx1, or Cre. Col2a1, Sox9 and Bapx1 were upregulated by Runx1 …
Runx1, Runx3, and T-bet Regulate the Conversion of Th17 to Th1 …
Runx1 is required for the survival of CD4 + T cells, in part by regulating IL-7Ra expression, and Runx1-deficient mice have a substantial reduction in peripheral CD4 + T cells ( Egawa et al.,...