
The role of m6A modification in the biological functions and
Feb 21, 2021 · In this review, we discuss how m6A RNA methylation influences both the physiological and pathological progressions of hematopoietic, central nervous and …
m6A RNA methylation: from mechanisms to therapeutic potential
We highlight advances in our understanding of the regulation of m 6 A deposition on mRNA and its context‐dependent effects on mRNA decay and translation, the role of m 6 A methylation of …
m 6 A RNA methylation: from mechanisms to therapeutic potential …
Feb 1, 2021 · We highlight advances in our understanding of the regulation of m 6 A deposition on mRNA and its context-dependent effects on mRNA decay and translation, the role of m 6 A …
Reading, writing and erasing mRNA methylation - Nature
Sep 13, 2019 · RNA methylation to form N6 -methyladenosine (m 6 A) in mRNA accounts for the most abundant mRNA internal modification and has emerged as a widespread regulatory …
RNA m6A methylation across the transcriptome - Cell Press
Feb 2, 2023 · Here, we review RNA m6A modification in the light of the recent appreciation of nuclear roles for m6A in regulating chromatin states and gene expression, as well as the …
m6A Modification in Coding and Non-coding RNAs: Roles and …
N6-methyladenosine (m6A) RNA modification emerges in recent years as a new layer of regulatory mechanism controlling gene expression in eukaryotes. As a reversible epigenetic …
Defining context-dependent m6A RNA methylomes in Arabidopsis
N6-Methyladenosine (m6A) prevalently occurs on cellular RNA across almost all kingdoms of life. Zhang et al. report a comprehensive m6A census of Arabidopsis development and response …
The role of m6A RNA methylation in human cancer - PMC
N6-methyladenosine (m6A) is identified as the most common, abundant and conserved internal transcriptional modification, especially within eukaryotic messenger RNAs (mRNAs). M6A …
Decoding the m6A epitranscriptomic landscape for …
Jan 18, 2025 · Epitranscriptomic modifications, particularly N6-methyladenosine (m6A), are crucial regulators of gene expression, influencing processes such as RNA stability, splicing, …
m6A RNA methylation: a pivotal regulator of tumor immunity and …
Feb 28, 2025 · m6A is an RNA methylation modification named for its presence at the sixth nitrogen atom of adenine in RNA. Discovered in the 1970s, m6A is widely distributed in …
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