Jul 27, 2022 · Evidence-based recommendations on placental growth factor (PLGF)-based testing to help diagnose suspected preterm pre-eclampsia. The tests are: DELFIA Xpress PLGF 1 2 3, DELFIA Xpress sFlt 1/PLGF 1 2 3 ratio, Elecsys immunoassay sFlt …

A new blood test (known as PLGF based tests) indicates whether the women has the disease and when used in women with suspected pre-eclampsia can reliably indicate who will need delivery soon.

Placental growth factor (PlGF) is an increasingly important player in the clinical management of pre-eclampsia. This review outlines the role of PlGF in human physiology but focuses specifically on the current understanding of PlGF’s function in …

May 4, 2019 · Our stepped-wedge cluster-randomised controlled trial provides evidence of the clinical effects of PlGF-based testing on the time to diagnosis and maternal and perinatal outcomes in women with suspected pre-eclampsia.

Jul 23, 2020 · Angiogenic biomarkers, including placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFlt-1), have been identified as valuable biomarkers for preterm pre-eclampsia, accelerating diagnosis and reducing maternal adverse outcomes by risk stratification, with enhanced surveillance for high-risk women.

Jul 11, 2022 · Maternal PlGF, sFlt-1 and sFlt-1/PlGF ratio show good performance for screening and diagnosing PE, for predicting development of PE in the short term, for monitoring established PE and for predicting other placenta-related disorders.

High-quality evidence now shows that this test, and the DELFIA Xpress sFlt-1/PLGF 1-2-3 ratio assay, have good accuracy for preterm pre-eclampsia. NICE previously recommended the Elecsys immunoassay sFlt-1/PLGF ratio and Triage PLGF Test to help rule out pre-eclampsia.

The value of PlGF and sFlt-1/PlGF as rule-out tests in the diagnosis and short-term prediction of PE has been clearly established in singleton pregnancies, outperforming traditional clinical parameters in determining time-to-delivery and predicting adverse perinatal outcomes.

May 8, 2024 · PlGF tests are ground-breaking new blood tests clinicians can use to help predict if a baby needs to be delivered due to pre-eclampsia in the late stages of pregnancy. The tests are usually used at 30 weeks and above.

PlGF-based testing to help diagnose suspected pre-eclampsia (Triage PlGF test, Elecsys immunoassay sFlt-1/PlGF ratio, DELFIA Xpress PlGF 1-2-3 test, and BRAHMS sFlt-1 Kryptor/BRAHMS PlGF plus Kryptor PE ratio) [Google Scholar]